I graduated in 2010 from the Aristotle University of Thessaloniki with a Ptychio in Biology, specialized in Molecular Biology, Genetics and Development.
Since 2010, I've been a member of GSfBS and IGSDHD and I have been enrolled in the M.Sc. in Biological Sciences and the Fast Track Masters/Doctoral program at the University of Cologne.

In December 2012 I recieved the M.Sc.. During my Master thesis in the laboratory of Prof. Dr. Brüning I investigated the role of constitutive c-Jun N-terminal kinase 1 (JNK1) activation in AgRP neurons.

During the rotation period, I worked on the following projects:

  • Lab of Dr. Praefcke: Purification and functional analysis of hGBP1
  • Lab of Prof. Dr. Brüning: Roles of SIRT2 in metabolic regulation
  • Lab of Prof. Dr. Pasparakis: The role of the IKK complex in heart metabolism.

Currently I am working on my PhD project in the lab of Prof. Dr. Brüning in the Institute for Genetics. I am using a mouse model of conditional mutagenesis to investigate the role of JNK1 in the central nervous system and how it can affect aging and aging associated diseases.

Acute selective ablation of rat insulin promoter-expressing (RIPHER) neurons defines their orexigenic nature.
Rother E, Belgardt BF, Tsaousidou E, Hampel B, Waisman A, Myers MG Jr, Brüning JC. Proceedings of Natural Academy of Sciences U S A (PNAS). 2012 Oct 30;109(44):18132-7. PMID:23064638

Poster in the Alumni Day 2012:
Constitutive activation of c-Jun-N terminal kinase (JNK)-1 in AgRP neurons is sufficient to impair energy and glucose homeostasis.